The transcription factor SKN-1 and detoxification gene ugt-22 alter albendazole efficacy in Caenorhabditis elegans
Parasitic nematodes infect over 1/4 th of the human population and are a major burden on livestock and crop production. Benzimidazole class anthelmintics are widely used to treat infections, but resistance is a widespread problem. Mutation of genes encoding the benzimidazole target β-tubulin is a we...
Main Authors: | Pauline Fontaine, Keith Choe |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2018-08-01
|
Series: | International Journal for Parasitology: Drugs and Drug Resistance |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211320718300137 |
Similar Items
-
The Skp1 Homologs SKR-1/2 Are Required for the Caenorhabditis elegans SKN-1 Antioxidant/Detoxification Response Independently of p38 MAPK.
by: Cheng-Wei Wu, et al.
Published: (2016-10-01) -
HIF-1 and SKN-1 coordinate the transcriptional response to hydrogen sulfide in Caenorhabditis elegans.
by: Dana L Miller, et al.
Published: (2011-01-01) -
The activation of the oxidative stress response transcription factor SKN-1 in Caenorhabditis elegans by mitis group streptococci.
by: Ali Naji, et al.
Published: (2018-01-01) -
skn-1 is required for interneuron sensory integration and foraging behavior in Caenorhabditis elegans.
by: Mark A Wilson, et al.
Published: (2017-01-01) -
Arginine methylation of SKN-1 promotes oxidative stress resistance in Caenorhabditis elegans
by: Hongyuan Li, et al.
Published: (2019-02-01)