A Burkholderia pseudomallei Outer Membrane Vesicle Vaccine Provides Cross Protection against Inhalational Glanders in Mice and Non-Human Primates

A Burkholderia pseudomallei Outer Membrane Vesicle Vaccine Provides Cross Protection against Inhalational Glanders in Mice and Non-Human Primates

Burkholderia mallei is a Gram-negative, non-motile, facultative intracellular bacillus and the causative agent of glanders, a highly contagious zoonotic disease. B. mallei is naturally resistant to multiple antibiotics and there is concern for its potential use as a bioweapon, making the development...

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Bibliographic Details
Main Authors: Sarah M. Baker, Christopher J. H. Davitt, Natalya Motyka, Nicole L. Kikendall, Kasi Russell-Lodrigue, Chad J. Roy, Lisa A. Morici
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Vaccines
Subjects:
Burkholderia mallei
persistence
bacteria
infection
glanders
outer membrane vesicles
vaccine
biodefense
Online Access:https://www.mdpi.com/2076-393X/5/4/49

Internet

https://www.mdpi.com/2076-393X/5/4/49

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