Exploring Flexibility of Progesterone Receptor Ligand Binding Domain Using Molecular Dynamics.
Progesterone receptor (PR), a member of nuclear receptor (NR) superfamily, plays a vital role for female reproductive tissue development, differentiation and maintenance. PR ligand, such as progesterone, induces conformation changes in PR ligand binding domain (LBD), thus mediates subsequent gene re...
Main Authors: | Liangzhen Zheng, Valerie Chunling Lin, Yuguang Mu |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5100906?pdf=render |
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