Effects of acute levodopa challenge on resting cerebral blood flow in Parkinson’s Disease patients assessed using pseudo-continuous arterial spin labeling

Effects of acute levodopa challenge on resting cerebral blood flow in Parkinson’s Disease patients assessed using pseudo-continuous arterial spin labeling

Introduction. Levodopa is the gold-standard for treatment of Parkinson’s disease (PD) related motor symptoms. In this study, we used pseudo-continuous arterial spin labeling (pCASL) to quantify changes in cerebral blood flow (CBF) after acute oral administration of levodopa in PD patients.Materials...

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Bibliographic Details
Main Authors: Yufen Chen, Peter Pressman, Tanya Simuni, Todd B. Parrish, Darren R. Gitelman
Format: Article
Language:English
Published: PeerJ Inc. 2015-11-01
Series:PeerJ
Subjects:
Cerebral blood flow
Levodopa
Arterial spin labeling
Parkinson’s disease
Pharmacological MRI
Online Access:https://peerj.com/articles/1381.pdf

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