Developing Novel G-Quadruplex Ligands: from Interaction with Nucleic Acids to Interfering with Nucleic Acid–Protein Interaction
G-quadruplex is a special secondary structure of nucleic acids in guanine-rich sequences of genome. G-quadruplexes have been proved to be involved in the regulation of replication, DNA damage repair, and transcription and translation of oncogenes or other cancer-related genes. Therefore, targeting G...
Main Authors: | Zhi-Yin Sun, Xiao-Na Wang, Sui-Qi Cheng, Xiao-Xuan Su, Tian-Miao Ou |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-01-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/24/3/396 |
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