Exploring mechanochemistry to turn organic bio-relevant molecules into metal-organic frameworks: a short review

• Main Authors: Vânia André, Sílvia Quaresma, João Luís Ferreira da Silva, M. Teresa Duarte
• Format: Article
• Language: English
• Published: Beilstein-Institut 2017-11-01
• Series: Beilstein Journal of Organic Chemistry
• Subjects: BioMOFs; drugs; green chemistry; mechanochemistry; organic based materials
• Online Access: https://doi.org/10.3762/bjoc.13.239

Mechanochemistry is a powerful and environmentally friendly synthetic technique successfully employed in different fields of synthetic chemistry. Application spans from organic to inorganic chemistry including the synthesis of coordination compounds. Metal-organic frameworks (MOFs) are a class of compounds with numerous applications, from which we highlight herein their application in the pharmaceutical field (BioMOFs), whose importance has been growing and is now assuming a relevant and promising domain. The need to find cleaner, greener and more energy and material-efficient synthetic procedures led to the use of mechanochemistry into the synthesis of BioMOFs.