Biomimetic Sensitive Elements for 2,4,6-Trinitrotoluene Tested on Multi-Layered Sensors

• Main Authors: Ana Mihaela GAVRILA, Tanta Verona IORDACHE, Carmen LAZAU, Traian ROTARIU, Ileana CERNICA, Hermine STROESCU, Mihai STOICA, Corina ORHA, Cornelia Elena BANDAS, Andrei SARBU
• Format: Article
• Language: English
• Published: MDPI AG 2020-03-01
• Series: Coatings
• Subjects: 2,4,6-trinitrotoluene; double meisenheimer complex; biomimetic sensitive elements; molecular imprinting; multilayered sensors; vapor state detection
• Online Access: https://www.mdpi.com/2079-6412/10/3/273

In spite of technological progress, most of the current techniques for 2,4,6-trinitrotoluene (TNT) detection are time consuming due to laborious sensor preparation. Thereby, the aim of this work was to enlarge the knowledge for preparing sensitive elements for TNT with the aid of molecular imprinting; a known technique used to deliver biomimetic materials. The study first depicts the auto-assembly mechanism of (TNT) with functional diamino-silanes (i.e., N-(2-aminoethyl)-3-aminopropyl methyl dimethoxysilane), via “double” Meisenheimer complexes. This mechanism is being described herein for the first time and applied further to obtain molecularly imprinted polymer (MIP) films for TNT recognition. For testing the potential application of films as chemical sensor elements, typical rebinding assays of TNT in a liquid state and the rebinding of TNT in a vapor state, using multilayered sensor chips composed of quartz-chromium (Cr)-gold (Au)-titanium oxide (TiO₂), were employed. Batch rebinding experiments have shown that thinner films were more efficient on retaining TNT molecules in the first five min, with a specificity of about 1.90. The quartz-Cr-Au-TiO₂-MIP capacitive sensors, tested in vapor state, registered short response times (less than 25 s), low sensitivity to humidity and high specificity for TNT.