Resolving Subcellular miRNA Trafficking and Turnover at Single-Molecule Resolution

Resolving Subcellular miRNA Trafficking and Turnover at Single-Molecule Resolution

Summary: Regulation of microRNA (miRNA) localization and stability is critical for their extensive cytoplasmic RNA silencing activity and emerging nuclear functions. Here, we have developed single-molecule fluorescence-based tools to assess the subcellular trafficking, integrity, and activity of miR...

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Bibliographic Details
Main Authors: Sethuramasundaram Pitchiaya, Laurie A. Heinicke, Jun I. Park, Elizabeth L. Cameron, Nils G. Walter
Format: Article
Language:English
Published: Elsevier 2017-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717304527

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