Obesity-associated metabolic syndrome spontaneously induces infiltration of pro-inflammatory macrophage in synovium and promotes osteoarthritis.
Epidemiological and experimental studies have established obesity to be an important risk factor for osteoarthritis (OA), however, the mechanisms underlying this link remains largely unknown. Here, we studied local inflammatory responses in metabolic-OA.Wistar rats were fed with control diet (CD) an...
Main Authors: | Antonia RuJia Sun, Sunil K Panchal, Thor Friis, Sunderajhan Sekar, Ross Crawford, Lindsay Brown, Yin Xiao, Indira Prasadam |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5578643?pdf=render |
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