Data on the potential impact of food supplements on the growth of mouse embryonic stem cells

The use of new compounds as dietary supplements is increasing, but little is known in terms of possible consequences of their use. Pluripotent stem cells are a promising research tool for citotoxicological research for evaluation of proliferation, cell death, pluripotency and differentiation. Using...

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Bibliographic Details
Main Authors: Marcelo Correia, Maria I. Sousa, Ana S. Rodrigues, Tânia Perestrelo, Sandro L. Pereira, Marcelo F. Ribeiro, João Ramalho-Santos
Format: Article
Language:English
Published: Elsevier 2016-06-01
Series:Data in Brief
Online Access:http://www.sciencedirect.com/science/article/pii/S2352340916302062
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Summary:The use of new compounds as dietary supplements is increasing, but little is known in terms of possible consequences of their use. Pluripotent stem cells are a promising research tool for citotoxicological research for evaluation of proliferation, cell death, pluripotency and differentiation. Using the mouse embryonic stem cell (mESC) model, we present data on three different compounds that have been proposed as new potential supplements for co-adjuvant disease treatments: kaempferol, berberine and Tauroursodeoxycholic acid (TUDCA). Cell number and viability were monitored following treatment with increased concentrations of each drug in pluripotent culture conditions. Keywords: Mouse embryonic stem cells, Kaempferol, Berberine, Tauroursodeoxycholic acid, Cell growth, Toxicology, Dietary supplements
ISSN:2352-3409