Data on the potential impact of food supplements on the growth of mouse embryonic stem cells

The use of new compounds as dietary supplements is increasing, but little is known in terms of possible consequences of their use. Pluripotent stem cells are a promising research tool for citotoxicological research for evaluation of proliferation, cell death, pluripotency and differentiation. Using...

Full description

Bibliographic Details
Main Authors: Marcelo Correia, Maria I. Sousa, Ana S. Rodrigues, Tânia Perestrelo, Sandro L. Pereira, Marcelo F. Ribeiro, João Ramalho-Santos
Format: Article
Language:English
Published: Elsevier 2016-06-01
Series:Data in Brief
Online Access:http://www.sciencedirect.com/science/article/pii/S2352340916302062
id doaj-954bb9bc6d2e47a5b4896a37c8e255ae
record_format Article
spelling doaj-954bb9bc6d2e47a5b4896a37c8e255ae2020-11-25T01:46:02ZengElsevierData in Brief2352-34092016-06-01711901195Data on the potential impact of food supplements on the growth of mouse embryonic stem cellsMarcelo Correia0Maria I. Sousa1Ana S. Rodrigues2Tânia Perestrelo3Sandro L. Pereira4Marcelo F. Ribeiro5João Ramalho-Santos6Ph.D. Programme in Experimental Biology and Biomedicine (PDBEB), CNC – Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal; Institute for Interdisciplinary Research (IIIUC), University of Coimbra, Coimbra, Portugal; Biology of Reproduction and Stem Cell Group, CNC – Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, PortugalBiology of Reproduction and Stem Cell Group, CNC – Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal; Department of Life Sciences, University of Coimbra, Coimbra, PortugalBiology of Reproduction and Stem Cell Group, CNC – Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal; Department of Life Sciences, University of Coimbra, Coimbra, PortugalPh.D. Programme in Experimental Biology and Biomedicine (PDBEB), CNC – Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal; Institute for Interdisciplinary Research (IIIUC), University of Coimbra, Coimbra, Portugal; Biology of Reproduction and Stem Cell Group, CNC – Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, PortugalBiology of Reproduction and Stem Cell Group, CNC – Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal; Department of Life Sciences, University of Coimbra, Coimbra, PortugalBiology of Reproduction and Stem Cell Group, CNC – Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal; Department of Life Sciences, University of Coimbra, Coimbra, PortugalBiology of Reproduction and Stem Cell Group, CNC – Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal; Department of Life Sciences, University of Coimbra, Coimbra, Portugal; Corresponding author at: Department of Life Sciences, University of Coimbra, Coimbra, Portugal.The use of new compounds as dietary supplements is increasing, but little is known in terms of possible consequences of their use. Pluripotent stem cells are a promising research tool for citotoxicological research for evaluation of proliferation, cell death, pluripotency and differentiation. Using the mouse embryonic stem cell (mESC) model, we present data on three different compounds that have been proposed as new potential supplements for co-adjuvant disease treatments: kaempferol, berberine and Tauroursodeoxycholic acid (TUDCA). Cell number and viability were monitored following treatment with increased concentrations of each drug in pluripotent culture conditions. Keywords: Mouse embryonic stem cells, Kaempferol, Berberine, Tauroursodeoxycholic acid, Cell growth, Toxicology, Dietary supplementshttp://www.sciencedirect.com/science/article/pii/S2352340916302062
collection DOAJ
language English
format Article
sources DOAJ
author Marcelo Correia
Maria I. Sousa
Ana S. Rodrigues
Tânia Perestrelo
Sandro L. Pereira
Marcelo F. Ribeiro
João Ramalho-Santos
spellingShingle Marcelo Correia
Maria I. Sousa
Ana S. Rodrigues
Tânia Perestrelo
Sandro L. Pereira
Marcelo F. Ribeiro
João Ramalho-Santos
Data on the potential impact of food supplements on the growth of mouse embryonic stem cells
Data in Brief
author_facet Marcelo Correia
Maria I. Sousa
Ana S. Rodrigues
Tânia Perestrelo
Sandro L. Pereira
Marcelo F. Ribeiro
João Ramalho-Santos
author_sort Marcelo Correia
title Data on the potential impact of food supplements on the growth of mouse embryonic stem cells
title_short Data on the potential impact of food supplements on the growth of mouse embryonic stem cells
title_full Data on the potential impact of food supplements on the growth of mouse embryonic stem cells
title_fullStr Data on the potential impact of food supplements on the growth of mouse embryonic stem cells
title_full_unstemmed Data on the potential impact of food supplements on the growth of mouse embryonic stem cells
title_sort data on the potential impact of food supplements on the growth of mouse embryonic stem cells
publisher Elsevier
series Data in Brief
issn 2352-3409
publishDate 2016-06-01
description The use of new compounds as dietary supplements is increasing, but little is known in terms of possible consequences of their use. Pluripotent stem cells are a promising research tool for citotoxicological research for evaluation of proliferation, cell death, pluripotency and differentiation. Using the mouse embryonic stem cell (mESC) model, we present data on three different compounds that have been proposed as new potential supplements for co-adjuvant disease treatments: kaempferol, berberine and Tauroursodeoxycholic acid (TUDCA). Cell number and viability were monitored following treatment with increased concentrations of each drug in pluripotent culture conditions. Keywords: Mouse embryonic stem cells, Kaempferol, Berberine, Tauroursodeoxycholic acid, Cell growth, Toxicology, Dietary supplements
url http://www.sciencedirect.com/science/article/pii/S2352340916302062
work_keys_str_mv AT marcelocorreia dataonthepotentialimpactoffoodsupplementsonthegrowthofmouseembryonicstemcells
AT mariaisousa dataonthepotentialimpactoffoodsupplementsonthegrowthofmouseembryonicstemcells
AT anasrodrigues dataonthepotentialimpactoffoodsupplementsonthegrowthofmouseembryonicstemcells
AT taniaperestrelo dataonthepotentialimpactoffoodsupplementsonthegrowthofmouseembryonicstemcells
AT sandrolpereira dataonthepotentialimpactoffoodsupplementsonthegrowthofmouseembryonicstemcells
AT marcelofribeiro dataonthepotentialimpactoffoodsupplementsonthegrowthofmouseembryonicstemcells
AT joaoramalhosantos dataonthepotentialimpactoffoodsupplementsonthegrowthofmouseembryonicstemcells
_version_ 1725021059725393920