Data on the potential impact of food supplements on the growth of mouse embryonic stem cells
The use of new compounds as dietary supplements is increasing, but little is known in terms of possible consequences of their use. Pluripotent stem cells are a promising research tool for citotoxicological research for evaluation of proliferation, cell death, pluripotency and differentiation. Using...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2016-06-01
|
Series: | Data in Brief |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352340916302062 |
id |
doaj-954bb9bc6d2e47a5b4896a37c8e255ae |
---|---|
record_format |
Article |
spelling |
doaj-954bb9bc6d2e47a5b4896a37c8e255ae2020-11-25T01:46:02ZengElsevierData in Brief2352-34092016-06-01711901195Data on the potential impact of food supplements on the growth of mouse embryonic stem cellsMarcelo Correia0Maria I. Sousa1Ana S. Rodrigues2Tânia Perestrelo3Sandro L. Pereira4Marcelo F. Ribeiro5João Ramalho-Santos6Ph.D. Programme in Experimental Biology and Biomedicine (PDBEB), CNC – Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal; Institute for Interdisciplinary Research (IIIUC), University of Coimbra, Coimbra, Portugal; Biology of Reproduction and Stem Cell Group, CNC – Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, PortugalBiology of Reproduction and Stem Cell Group, CNC – Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal; Department of Life Sciences, University of Coimbra, Coimbra, PortugalBiology of Reproduction and Stem Cell Group, CNC – Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal; Department of Life Sciences, University of Coimbra, Coimbra, PortugalPh.D. Programme in Experimental Biology and Biomedicine (PDBEB), CNC – Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal; Institute for Interdisciplinary Research (IIIUC), University of Coimbra, Coimbra, Portugal; Biology of Reproduction and Stem Cell Group, CNC – Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, PortugalBiology of Reproduction and Stem Cell Group, CNC – Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal; Department of Life Sciences, University of Coimbra, Coimbra, PortugalBiology of Reproduction and Stem Cell Group, CNC – Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal; Department of Life Sciences, University of Coimbra, Coimbra, PortugalBiology of Reproduction and Stem Cell Group, CNC – Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal; Department of Life Sciences, University of Coimbra, Coimbra, Portugal; Corresponding author at: Department of Life Sciences, University of Coimbra, Coimbra, Portugal.The use of new compounds as dietary supplements is increasing, but little is known in terms of possible consequences of their use. Pluripotent stem cells are a promising research tool for citotoxicological research for evaluation of proliferation, cell death, pluripotency and differentiation. Using the mouse embryonic stem cell (mESC) model, we present data on three different compounds that have been proposed as new potential supplements for co-adjuvant disease treatments: kaempferol, berberine and Tauroursodeoxycholic acid (TUDCA). Cell number and viability were monitored following treatment with increased concentrations of each drug in pluripotent culture conditions. Keywords: Mouse embryonic stem cells, Kaempferol, Berberine, Tauroursodeoxycholic acid, Cell growth, Toxicology, Dietary supplementshttp://www.sciencedirect.com/science/article/pii/S2352340916302062 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Marcelo Correia Maria I. Sousa Ana S. Rodrigues Tânia Perestrelo Sandro L. Pereira Marcelo F. Ribeiro João Ramalho-Santos |
spellingShingle |
Marcelo Correia Maria I. Sousa Ana S. Rodrigues Tânia Perestrelo Sandro L. Pereira Marcelo F. Ribeiro João Ramalho-Santos Data on the potential impact of food supplements on the growth of mouse embryonic stem cells Data in Brief |
author_facet |
Marcelo Correia Maria I. Sousa Ana S. Rodrigues Tânia Perestrelo Sandro L. Pereira Marcelo F. Ribeiro João Ramalho-Santos |
author_sort |
Marcelo Correia |
title |
Data on the potential impact of food supplements on the growth of mouse embryonic stem cells |
title_short |
Data on the potential impact of food supplements on the growth of mouse embryonic stem cells |
title_full |
Data on the potential impact of food supplements on the growth of mouse embryonic stem cells |
title_fullStr |
Data on the potential impact of food supplements on the growth of mouse embryonic stem cells |
title_full_unstemmed |
Data on the potential impact of food supplements on the growth of mouse embryonic stem cells |
title_sort |
data on the potential impact of food supplements on the growth of mouse embryonic stem cells |
publisher |
Elsevier |
series |
Data in Brief |
issn |
2352-3409 |
publishDate |
2016-06-01 |
description |
The use of new compounds as dietary supplements is increasing, but little is known in terms of possible consequences of their use. Pluripotent stem cells are a promising research tool for citotoxicological research for evaluation of proliferation, cell death, pluripotency and differentiation. Using the mouse embryonic stem cell (mESC) model, we present data on three different compounds that have been proposed as new potential supplements for co-adjuvant disease treatments: kaempferol, berberine and Tauroursodeoxycholic acid (TUDCA). Cell number and viability were monitored following treatment with increased concentrations of each drug in pluripotent culture conditions. Keywords: Mouse embryonic stem cells, Kaempferol, Berberine, Tauroursodeoxycholic acid, Cell growth, Toxicology, Dietary supplements |
url |
http://www.sciencedirect.com/science/article/pii/S2352340916302062 |
work_keys_str_mv |
AT marcelocorreia dataonthepotentialimpactoffoodsupplementsonthegrowthofmouseembryonicstemcells AT mariaisousa dataonthepotentialimpactoffoodsupplementsonthegrowthofmouseembryonicstemcells AT anasrodrigues dataonthepotentialimpactoffoodsupplementsonthegrowthofmouseembryonicstemcells AT taniaperestrelo dataonthepotentialimpactoffoodsupplementsonthegrowthofmouseembryonicstemcells AT sandrolpereira dataonthepotentialimpactoffoodsupplementsonthegrowthofmouseembryonicstemcells AT marcelofribeiro dataonthepotentialimpactoffoodsupplementsonthegrowthofmouseembryonicstemcells AT joaoramalhosantos dataonthepotentialimpactoffoodsupplementsonthegrowthofmouseembryonicstemcells |
_version_ |
1725021059725393920 |