Transcriptional profiling of non-small cell lung cancer cells with activating EGFR somatic mutations.

Transcriptional profiling of non-small cell lung cancer cells with activating EGFR somatic mutations.

Activating somatic mutations in epidermal growth factor receptor (EGFR) confer unique biologic features to non-small cell lung cancer (NSCLC) cells, but the transcriptional mediators of EGFR in this subgroup of NSCLC have not been fully elucidated.Here we used genetic and pharmacologic approaches to...

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Bibliographic Details
Main Authors: Kuicheon Choi, Chad J Creighton, David Stivers, Nobukazu Fujimoto, Jonathan M Kurie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2080626?pdf=render

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http://europepmc.org/articles/PMC2080626?pdf=render

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