Antiproliferative Activity of Hinokitiol, a Tropolone Derivative, Is Mediated via the Inductions of p-JNK and p-PLCγ1 Signaling in PDGF-BB-Stimulated Vascular Smooth Muscle Cells
Abnormal proliferation of vascular smooth muscle cells (VSMCs) is important in the pathogenesis of vascular disorders such as atherosclerosis and restenosis. Hinokitiol, a tropolone derivative found in Chamacyparis taiwanensis, has been found to exhibit anticancer activity in a variety of cancers t...
Main Authors: | Po-Sheng Yang, Meng-Jiy Wang, Thanasekaran Jayakumar, Duen-Suey Chou, Ching-Ya Ko, Ming-Jen Hsu, Cheng-Ying Hsieh |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2015-05-01
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Series: | Molecules |
Subjects: | |
Online Access: | http://www.mdpi.com/1420-3049/20/5/8198 |
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