Resolution of Laryngeal Oedema in a Patient with Acquired C1-Inhibitor Deficiency. A Case Report

Laryngeal oedema caused by acquired angioedema due to C1-inhibitor deficiency (C1-INH-AAE) is a life-threatening condition. The swelling is bradykinin mediated and will not respond to the usual treatment with antihistamines, corticosteroids, or epinephrine. Instead, kallikrein-bradykinin-targeted th...

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Main Authors: Bara Noémi-Anna, Nadasan Valentin
Format: Article
Language:English
Published: Sciendo 2021-05-01
Series:The Journal of Critical Care Medicine
Subjects:
Online Access:https://doi.org/10.2478/jccm-2021-0003
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spelling doaj-95a41541df0f41f69febebd4bcfb77ce2021-09-06T19:41:34ZengSciendoThe Journal of Critical Care Medicine2393-18172021-05-017213614010.2478/jccm-2021-0003Resolution of Laryngeal Oedema in a Patient with Acquired C1-Inhibitor Deficiency. A Case ReportBara Noémi-Anna0Nadasan Valentin1Hereditary Angioedema Expertise Centre, Sangeorgiu De Mures, MuresRomaniaGeorge Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, MuresRomaniaLaryngeal oedema caused by acquired angioedema due to C1-inhibitor deficiency (C1-INH-AAE) is a life-threatening condition. The swelling is bradykinin mediated and will not respond to the usual treatment with antihistamines, corticosteroids, or epinephrine. Instead, kallikrein-bradykinin-targeted therapies should be used promptly to prevent asphyxiation.https://doi.org/10.2478/jccm-2021-0003acquired c1-inhibitor deficiencylaryngeal oedemaasphyxiationmonoclonal gammopathy of uncertain significanceemergency care treatment plan
collection DOAJ
language English
format Article
sources DOAJ
author Bara Noémi-Anna
Nadasan Valentin
spellingShingle Bara Noémi-Anna
Nadasan Valentin
Resolution of Laryngeal Oedema in a Patient with Acquired C1-Inhibitor Deficiency. A Case Report
The Journal of Critical Care Medicine
acquired c1-inhibitor deficiency
laryngeal oedema
asphyxiation
monoclonal gammopathy of uncertain significance
emergency care treatment plan
author_facet Bara Noémi-Anna
Nadasan Valentin
author_sort Bara Noémi-Anna
title Resolution of Laryngeal Oedema in a Patient with Acquired C1-Inhibitor Deficiency. A Case Report
title_short Resolution of Laryngeal Oedema in a Patient with Acquired C1-Inhibitor Deficiency. A Case Report
title_full Resolution of Laryngeal Oedema in a Patient with Acquired C1-Inhibitor Deficiency. A Case Report
title_fullStr Resolution of Laryngeal Oedema in a Patient with Acquired C1-Inhibitor Deficiency. A Case Report
title_full_unstemmed Resolution of Laryngeal Oedema in a Patient with Acquired C1-Inhibitor Deficiency. A Case Report
title_sort resolution of laryngeal oedema in a patient with acquired c1-inhibitor deficiency. a case report
publisher Sciendo
series The Journal of Critical Care Medicine
issn 2393-1817
publishDate 2021-05-01
description Laryngeal oedema caused by acquired angioedema due to C1-inhibitor deficiency (C1-INH-AAE) is a life-threatening condition. The swelling is bradykinin mediated and will not respond to the usual treatment with antihistamines, corticosteroids, or epinephrine. Instead, kallikrein-bradykinin-targeted therapies should be used promptly to prevent asphyxiation.
topic acquired c1-inhibitor deficiency
laryngeal oedema
asphyxiation
monoclonal gammopathy of uncertain significance
emergency care treatment plan
url https://doi.org/10.2478/jccm-2021-0003
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