Alpha-Synuclein: Mechanisms of Release and Pathology Progression in Synucleinopathies
The accumulation of misfolded alpha-synuclein (aSyn) throughout the brain, as Lewy pathology, is a phenomenon central to Parkinson’s disease (PD) pathogenesis. The stereotypical distribution and evolution of the pathology during disease is often attributed to the cell-to-cell transmission of aSyn be...
Main Authors: | Inês C. Brás, Tiago F. Outeiro |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-02-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/10/2/375 |
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