Optimized low‐dose combinatorial drug treatment boosts selectivity and efficacy of colorectal carcinoma treatment
The current standard of care for colorectal cancer (CRC) is a combination of chemotherapeutics, often supplemented with targeted biological drugs. An urgent need exists for improved drug efficacy and minimized side effects, especially at late‐stage disease. We employed the phenotypically driven ther...
Main Authors: | Marloes Zoetemelk, George M. Ramzy, Magdalena Rausch, Thibaud Koessler, Judy R. vanBeijnum, Andrea Weiss, Valentin Mieville, Sander R. Piersma, Richard R. deHaas, Céline Delucinge‐Vivier, Axel Andres, Christian Toso, Alexander A. Henneman, Simone Ragusa, Tatiana V. Petrova, Mylène Docquier, Thomas A. McKee, Connie R. Jimenez, Youssef Daali, Arjan W. Griffioen, Laura Rubbia‐Brandt, Pierre‐Yves Dietrich, Patrycja Nowak‐Sliwinska |
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Format: | Article |
Language: | English |
Published: |
Wiley
2020-11-01
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Series: | Molecular Oncology |
Subjects: | |
Online Access: | https://doi.org/10.1002/1878-0261.12797 |
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