A Family of Salmonella Type III Secretion Effector Proteins Selectively Targets the NF-κB Signaling Pathway to Preserve Host Homeostasis.
Microbial infections usually lead to host innate immune responses and inflammation. These responses most often limit pathogen replication although they can also result in host-tissue damage. The enteropathogenic bacteria Salmonella Typhimurium utilizes a type III secretion system to induce intestina...
Main Authors: | Hui Sun, Jana Kamanova, Maria Lara-Tejero, Jorge E Galán |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-03-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC4775039?pdf=render |
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