ANTIPHOSPHOLIPID ANTIBODIES, THEIR PATHOGENETIC AND DIAGNOSTIC ISSUES OBSTETRIC PRACTICE

ANTIPHOSPHOLIPID ANTIBODIES, THEIR PATHOGENETIC AND DIAGNOSTIC ISSUES OBSTETRIC PRACTICE

Not only thrombotic, but also “non-thrombotic” mechanisms of antiphospholipid antibodies are being actively studied in regard to their impact on the structure of reproductive losses and other complications of pregnancy. Non-thrombotic effects of APA include the damage of cells, the induction of apop...

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Main Authors: V. O. Bitsadze, D. Kh. Khizroeva, N. A. Makatsariya, E. S. Egorova, S. M. Baymuradova, T. Ya. Mashkova
Format: Article
Language:Russian
Published: IRBIS LLC 2016-06-01
Series:Акушерство, гинекология и репродукция
Subjects:
antiphospholipid antibodies
antiphospholipid syndrome
complications of pregnancy
catastrophis antiphospholipid syndrome
Online Access:https://www.gynecology.su/jour/article/view/65
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spelling doaj-95d5a2ebc11e4f9a8a524aeed8c958602021-07-28T13:44:37ZrusIRBIS LLCАкушерство, гинекология и репродукция2313-73472500-31942016-06-0182396063ANTIPHOSPHOLIPID ANTIBODIES, THEIR PATHOGENETIC AND DIAGNOSTIC ISSUES OBSTETRIC PRACTICEV. O. Bitsadze0D. Kh. Khizroeva1N. A. Makatsariya2E. S. Egorova3S. M. Baymuradova4T. Ya. Mashkova5First Moscow State Medical Sechenov University of the Ministry of Health Russian FederationFirst Moscow State Medical Sechenov University of the Ministry of Health Russian FederationFirst Moscow State Medical Sechenov University of the Ministry of Health Russian FederationFirst Moscow State Medical Sechenov University of the Ministry of Health Russian FederationFirst Moscow State Medical Sechenov University of the Ministry of Health Russian FederationFirst Moscow State Medical Sechenov University of the Ministry of Health Russian FederationNot only thrombotic, but also “non-thrombotic” mechanisms of antiphospholipid antibodies are being actively studied in regard to their impact on the structure of reproductive losses and other complications of pregnancy. Non-thrombotic effects of APA include the damage of cells, the induction of apoptosis, the inhibition of proliferation, the suppression of human chorionic gonadotropin, the interference to the invasion of the trophoblast, and defectsof differentiation of the endometrium. Thrombotic effects are: widespread thrombosis, placental infarction, disruption of the annexin barrier, and anti-b2GPI and APC resistance.https://www.gynecology.su/jour/article/view/65antiphospholipid antibodiesantiphospholipid syndromecomplications of pregnancycatastrophis antiphospholipid syndrome
collection DOAJ
language Russian
format Article
sources DOAJ
author V. O. Bitsadze
D. Kh. Khizroeva
N. A. Makatsariya
E. S. Egorova
S. M. Baymuradova
T. Ya. Mashkova
spellingShingle V. O. Bitsadze
D. Kh. Khizroeva
N. A. Makatsariya
E. S. Egorova
S. M. Baymuradova
T. Ya. Mashkova
ANTIPHOSPHOLIPID ANTIBODIES, THEIR PATHOGENETIC AND DIAGNOSTIC ISSUES OBSTETRIC PRACTICE
Акушерство, гинекология и репродукция
antiphospholipid antibodies
antiphospholipid syndrome
complications of pregnancy
catastrophis antiphospholipid syndrome
author_facet V. O. Bitsadze
D. Kh. Khizroeva
N. A. Makatsariya
E. S. Egorova
S. M. Baymuradova
T. Ya. Mashkova
author_sort V. O. Bitsadze
title ANTIPHOSPHOLIPID ANTIBODIES, THEIR PATHOGENETIC AND DIAGNOSTIC ISSUES OBSTETRIC PRACTICE
title_short ANTIPHOSPHOLIPID ANTIBODIES, THEIR PATHOGENETIC AND DIAGNOSTIC ISSUES OBSTETRIC PRACTICE
title_full ANTIPHOSPHOLIPID ANTIBODIES, THEIR PATHOGENETIC AND DIAGNOSTIC ISSUES OBSTETRIC PRACTICE
title_fullStr ANTIPHOSPHOLIPID ANTIBODIES, THEIR PATHOGENETIC AND DIAGNOSTIC ISSUES OBSTETRIC PRACTICE
title_full_unstemmed ANTIPHOSPHOLIPID ANTIBODIES, THEIR PATHOGENETIC AND DIAGNOSTIC ISSUES OBSTETRIC PRACTICE
title_sort antiphospholipid antibodies, their pathogenetic and diagnostic issues obstetric practice
publisher IRBIS LLC
series Акушерство, гинекология и репродукция
issn 2313-7347
2500-3194
publishDate 2016-06-01
description Not only thrombotic, but also “non-thrombotic” mechanisms of antiphospholipid antibodies are being actively studied in regard to their impact on the structure of reproductive losses and other complications of pregnancy. Non-thrombotic effects of APA include the damage of cells, the induction of apoptosis, the inhibition of proliferation, the suppression of human chorionic gonadotropin, the interference to the invasion of the trophoblast, and defectsof differentiation of the endometrium. Thrombotic effects are: widespread thrombosis, placental infarction, disruption of the annexin barrier, and anti-b2GPI and APC resistance.
topic antiphospholipid antibodies
antiphospholipid syndrome
complications of pregnancy
catastrophis antiphospholipid syndrome
url https://www.gynecology.su/jour/article/view/65
work_keys_str_mv AT vobitsadze antiphospholipidantibodiestheirpathogeneticanddiagnosticissuesobstetricpractice
AT dkhkhizroeva antiphospholipidantibodiestheirpathogeneticanddiagnosticissuesobstetricpractice
AT namakatsariya antiphospholipidantibodiestheirpathogeneticanddiagnosticissuesobstetricpractice
AT esegorova antiphospholipidantibodiestheirpathogeneticanddiagnosticissuesobstetricpractice
AT smbaymuradova antiphospholipidantibodiestheirpathogeneticanddiagnosticissuesobstetricpractice
AT tyamashkova antiphospholipidantibodiestheirpathogeneticanddiagnosticissuesobstetricpractice
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