Syntheses of Quinazoline-2,4-dione Alkaloids and Analogues from Mexican Zanthoxylum Species â€

Syntheses of Quinazoline-2,4-dione Alkaloids and Analogues from Mexican Zanthoxylum Species â€

Quinazolinone and quinazolinedione derivatives are of considerable interest due to their wide array of pharmacological properties. In this paper we report the synthesis of ten quinazolinediones. The previous isolation of two of these compounds, namely 1-methyl-3-(2'-phenylethyl)-1H,3H-quinazoli...

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Bibliographic Details
Main Authors: R. Somanathan, K. Espinoza, I. A. Rivero
Format: Article
Language:English
Published: MDPI AG 2004-06-01
Series:Molecules
Subjects:
Quinazoline-2
4-dione
alkaloids
triphosgene
anti-hypertensive activity.
Online Access:http://www.mdpi.com/1420-3049/9/7/609/
Description
Summary:Quinazolinone and quinazolinedione derivatives are of considerable interest due to their wide array of pharmacological properties. In this paper we report the synthesis of ten quinazolinediones. The previous isolation of two of these compounds, namely 1-methyl-3-(2'-phenylethyl)-1H,3H-quinazoline-2,4-dione and 1-methyl-3-[2'-(4'- methoxyphenyl)ethyl]-lH,3H-quinazoline-2,4-dione, from the seed husks of Mexican Zanthoxylum species has been reported
ISSN:1420-3049

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