Peptide Uptake Is Essential for Borrelia burgdorferi Viability and Involves Structural and Regulatory Complexity of its Oligopeptide Transporter
Borrelia burgdorferi is an extreme amino acid (AA) auxotroph whose genome encodes few free AA transporters and an elaborate oligopeptide transport system (B. burgdorferi Opp [BbOpp]). BbOpp consists of five oligopeptide-binding proteins (OBPs), two heterodimeric permeases, and a heterodimeric nucleo...
Main Authors: | Ashley M. Groshong, Abhishek Dey, Irina Bezsonova, Melissa J. Caimano, Justin D. Radolf, Steven J. Projan |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2017-12-01
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Series: | mBio |
Online Access: | http://mbio.asm.org/cgi/content/full/8/6/e02047-17 |
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