Complex I-associated hydrogen peroxide production is decreased and electron transport chain enzyme activities are altered in n-3 enriched fat-1 mice.

Complex I-associated hydrogen peroxide production is decreased and electron transport chain enzyme activities are altered in n-3 enriched fat-1 mice.

The polyunsaturated nature of n-3 fatty acids makes them prone to oxidative damage. However, it is not clear if n-3 fatty acids are simply a passive site for oxidative attack or if they also modulate mitochondrial reactive oxygen species (ROS) production. The present study used fat-1 transgenic mice...

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Bibliographic Details
Main Authors: Kevork Hagopian, Kristina L Weber, Darren T Hwee, Alison L Van Eenennaam, Guillermo López-Lluch, José M Villalba, Isabel Burón, Plácido Navas, J Bruce German, Steven M Watkins, Yana Chen, Alfreda Wei, Roger B McDonald, Jon J Ramsey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2938348?pdf=render

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