Tailoring a Global Iron Regulon to a Uropathogen

Host iron restriction is a common mechanism for limiting the growth of pathogens. We compared the regulatory network controlled by Fur in uropathogenic E. coli (UPEC) to that of nonpathogenic E. coli K-12 to uncover strategies that pathogenic bacteria use to overcome iron limitation. Although iron h...

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Bibliographic Details
Main Authors: Rajdeep Banerjee, Erin Weisenhorn, Kevin J. Schwartz, Kevin S. Myers, Jeremy D. Glasner, Nicole T. Perna, Joshua J. Coon, Rodney A. Welch, Patricia J. Kiley
Format: Article
Language:English
Published: American Society for Microbiology 2020-03-01
Series:mBio
Subjects:
fur
Online Access:https://doi.org/10.1128/mBio.00351-20

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