Off-label uses of etanercept in dermatology

Off-label uses of etanercept in dermatology

Tumour necrosis factor alpha (TNFα) is a key molecule involved in the inflammatory response and thus related to the pathogenesis of several autoimmune and autoinflammatory diseases. The blockade of TNF receptor (etanercept main effect) has been successfully used in psoriasis and psoriatic arthritis,...

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Bibliographic Details
Main Authors: Andrés Tirado-Sánchez, Victoria de la Fuente-García, Rosa María Ponce-Olivera
Format: Article
Language:English
Published: Permanyer 2016-01-01
Series:Revista Médica del Hospital General de México
Subjects:
Etanercept
Skin disease
Treatment
Online Access:http://www.sciencedirect.com/science/article/pii/S018510631500092X
Description
Summary:Tumour necrosis factor alpha (TNFα) is a key molecule involved in the inflammatory response and thus related to the pathogenesis of several autoimmune and autoinflammatory diseases. The blockade of TNF receptor (etanercept main effect) has been successfully used in psoriasis and psoriatic arthritis, among other rheumatologic diseases. The only approved indication for etanercept in dermatological disease is plaque psoriasis; however, the literature is full of case reports and case series where etanercept was used off-label, sometimes successfully. We review some of these indications.
ISSN:0185-1063

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