β-Catenin and FGFR2 regulate postnatal rosette-based adrenocortical morphogenesis

Multicellular rosettes are known to mediate complex cellular reorganization such as epithelial folding and branching during embryonal organogenesis. Here the authors show that rosette formation regulated by β-Catenin and FGFR2 mediate postnatal adrenal cortex zona glomerulosa morphogenesis.

Bibliographic Details
Main Authors:	Sining Leng, Emanuele Pignatti, Radhika S. Khetani, Manasvi S. Shah, Simiao Xu, Ji Miao, Makoto M. Taketo, Felix Beuschlein, Paula Q. Barrett, Diana L. Carlone, David T. Breault
Format:	Article
Language:	English
Published:	Nature Publishing Group 2020-04-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-020-15332-7

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spelling	doaj-964dbe99eb3a48cf943bd37deee261d22021-05-11T08:56:42ZengNature Publishing GroupNature Communications2041-17232020-04-0111111410.1038/s41467-020-15332-7β-Catenin and FGFR2 regulate postnatal rosette-based adrenocortical morphogenesisSining Leng0Emanuele Pignatti1Radhika S. Khetani2Manasvi S. Shah3Simiao Xu4Ji Miao5Makoto M. Taketo6Felix Beuschlein7Paula Q. Barrett8Diana L. Carlone9David T. Breault10Division of Endocrinology, Boston Children’s HospitalDivision of Endocrinology, Boston Children’s HospitalDepartment of Biostatistics, Harvard T.H. Chan School of Public HealthDivision of Endocrinology, Boston Children’s HospitalDivision of Endocrinology, Boston Children’s HospitalDivision of Endocrinology, Boston Children’s HospitalDivision of Experimental Therapeutics, Graduate School of Medicine, Kyoto UniversityDepartment of Endocrinology, Diabetology and Clinical Nutrition, UniversitätsSpital ZürichDepartments of Pharmacology, University of VirginiaDivision of Endocrinology, Boston Children’s HospitalDivision of Endocrinology, Boston Children’s HospitalMulticellular rosettes are known to mediate complex cellular reorganization such as epithelial folding and branching during embryonal organogenesis. Here the authors show that rosette formation regulated by β-Catenin and FGFR2 mediate postnatal adrenal cortex zona glomerulosa morphogenesis.https://doi.org/10.1038/s41467-020-15332-7
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Sining Leng Emanuele Pignatti Radhika S. Khetani Manasvi S. Shah Simiao Xu Ji Miao Makoto M. Taketo Felix Beuschlein Paula Q. Barrett Diana L. Carlone David T. Breault
spellingShingle	Sining Leng Emanuele Pignatti Radhika S. Khetani Manasvi S. Shah Simiao Xu Ji Miao Makoto M. Taketo Felix Beuschlein Paula Q. Barrett Diana L. Carlone David T. Breault β-Catenin and FGFR2 regulate postnatal rosette-based adrenocortical morphogenesis Nature Communications
author_facet	Sining Leng Emanuele Pignatti Radhika S. Khetani Manasvi S. Shah Simiao Xu Ji Miao Makoto M. Taketo Felix Beuschlein Paula Q. Barrett Diana L. Carlone David T. Breault
author_sort	Sining Leng
title	β-Catenin and FGFR2 regulate postnatal rosette-based adrenocortical morphogenesis
title_short	β-Catenin and FGFR2 regulate postnatal rosette-based adrenocortical morphogenesis
title_full	β-Catenin and FGFR2 regulate postnatal rosette-based adrenocortical morphogenesis
title_fullStr	β-Catenin and FGFR2 regulate postnatal rosette-based adrenocortical morphogenesis
title_full_unstemmed	β-Catenin and FGFR2 regulate postnatal rosette-based adrenocortical morphogenesis
title_sort	β-catenin and fgfr2 regulate postnatal rosette-based adrenocortical morphogenesis
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2020-04-01
description	Multicellular rosettes are known to mediate complex cellular reorganization such as epithelial folding and branching during embryonal organogenesis. Here the authors show that rosette formation regulated by β-Catenin and FGFR2 mediate postnatal adrenal cortex zona glomerulosa morphogenesis.
url	https://doi.org/10.1038/s41467-020-15332-7
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β-Catenin and FGFR2 regulate postnatal rosette-based adrenocortical morphogenesis

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