CD4<sup>+</sup> T Cells Induced by Tuberculosis Subunit Vaccine H1 Can Improve the HIV-1 Env Humoral Response by Intrastructural Help

CD4<sup>+</sup> T Cells Induced by Tuberculosis Subunit Vaccine H1 Can Improve the HIV-1 Env Humoral Response by Intrastructural Help

The induction of a potent and long-lasting, broadly neutralizing antibody response is one of the most promising approaches in HIV-1 vaccination. Recently, we demonstrated that Gag-specific T helper cells induced by DNA priming can enhance and modulate the HIV Env-specific B cell response upon virus-...

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Bibliographic Details
Main Authors: Stephan Klessing, Vladimir Temchura, Pierre Tannig, Antonia Sophia Peter, Dennis Christensen, Roland Lang, Klaus Überla
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Vaccines
Subjects:
HIV-1 vaccine
intrastructural help
H1 tuberculosis vaccine
IgG isotype modulation
Online Access:https://www.mdpi.com/2076-393X/8/4/604

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