Skin Reaction in Radiation Therapy for Breast Cancer
Introduction The first medical intervention for many breast cancer patients is breast conserving surgery (BCS) and/or modified radical mastectomy (MRM). Most of these patients undergo radiation therapy, following surgery. The most common side-effect of breast radiotherapy is skin damage. In the pres...
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doaj-9686899bc7554a8390a2cc2e56f57ba12020-11-24T21:24:54ZengMashhad University of Medical SciencesIranian Journal of Medical Physics2345-36722345-36722014-11-0111431632110.22038/ijmp.2014.35683568Skin Reaction in Radiation Therapy for Breast CancerBagher Farhood0Seyed Rabie Mahdavi1Mohammad Hasan Emranpour2Kamal Mohammadi Asl3Navid Nekoui4Courtney Knaup5Medical Physics Department, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranMedical Physics Department, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, IranShahid Rajaie Babolsar Radiotherapy Center, Babolsar, IranDepartemant of Computer Engineering and Information Technology, Payame Noor University, Tehran, IranDepartment of Statistics, Mashhad University of Medical Sciences, Mashhad, IranComprehensive Cancer Centers of Nevada, Las Vegas, Nevada, USAIntroduction The first medical intervention for many breast cancer patients is breast conserving surgery (BCS) and/or modified radical mastectomy (MRM). Most of these patients undergo radiation therapy, following surgery. The most common side-effect of breast radiotherapy is skin damage. In the present study, the severity of acute skin changes and the underlying causes were investigated in patients undergoing BCS and radiotherapy. Materials and Methods This prospective, cohort study was performed on 31 female patients, undergoing breast surgery therapy at Shahid Rajaie Babolsar Radiotherapy Center from September 2011 to July 2012. A questionnaire was designed, including the patient’s characteristics, details of radiotherapy technique, and skin damage; the questionnaire was completed for each patient. The obtained results were analysed by performing ANOVA and Fisher's exact tests. Complications were graded using the radiation therapy oncology group (RTOG) scale. Results Grade 0 or 4 of skin damage was observed in none of the patients. Among the evaluated patients, 58%, 35.5%, and 6.5% of the patients had grade 1, grade 2, and grade 3 of skin damage, respectively. There was no statistically significant relationship between regional skin burns and factors such as average tangential field size, internal mammary field, chemotherapy, prior history of diseases, tamoxifen use, previous radiotherapy in breast area, or skin type (p>0.05). However, there was a significant relationship between skin burns and presence of supraclavicular field (p=0.05). Conclusion Considering the significant relationship between skin burn and supraclavicular field, special attention needs to be paid to factors affecting the treatment planning of supraclavicular field such as field size and photon energy.http://ijmp.mums.ac.ir/article_3568_87ce7e79549d61eb0eb0515cd94739d7.pdfBreast cancerRadiotherapySkin BurnsBreast Conserving SurgerySurgery |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Bagher Farhood Seyed Rabie Mahdavi Mohammad Hasan Emranpour Kamal Mohammadi Asl Navid Nekoui Courtney Knaup |
spellingShingle |
Bagher Farhood Seyed Rabie Mahdavi Mohammad Hasan Emranpour Kamal Mohammadi Asl Navid Nekoui Courtney Knaup Skin Reaction in Radiation Therapy for Breast Cancer Iranian Journal of Medical Physics Breast cancer Radiotherapy Skin Burns Breast Conserving Surgery Surgery |
author_facet |
Bagher Farhood Seyed Rabie Mahdavi Mohammad Hasan Emranpour Kamal Mohammadi Asl Navid Nekoui Courtney Knaup |
author_sort |
Bagher Farhood |
title |
Skin Reaction in Radiation Therapy for Breast Cancer |
title_short |
Skin Reaction in Radiation Therapy for Breast Cancer |
title_full |
Skin Reaction in Radiation Therapy for Breast Cancer |
title_fullStr |
Skin Reaction in Radiation Therapy for Breast Cancer |
title_full_unstemmed |
Skin Reaction in Radiation Therapy for Breast Cancer |
title_sort |
skin reaction in radiation therapy for breast cancer |
publisher |
Mashhad University of Medical Sciences |
series |
Iranian Journal of Medical Physics |
issn |
2345-3672 2345-3672 |
publishDate |
2014-11-01 |
description |
Introduction The first medical intervention for many breast cancer patients is breast conserving surgery (BCS) and/or modified radical mastectomy (MRM). Most of these patients undergo radiation therapy, following surgery. The most common side-effect of breast radiotherapy is skin damage. In the present study, the severity of acute skin changes and the underlying causes were investigated in patients undergoing BCS and radiotherapy. Materials and Methods This prospective, cohort study was performed on 31 female patients, undergoing breast surgery therapy at Shahid Rajaie Babolsar Radiotherapy Center from September 2011 to July 2012. A questionnaire was designed, including the patient’s characteristics, details of radiotherapy technique, and skin damage; the questionnaire was completed for each patient. The obtained results were analysed by performing ANOVA and Fisher's exact tests. Complications were graded using the radiation therapy oncology group (RTOG) scale. Results Grade 0 or 4 of skin damage was observed in none of the patients. Among the evaluated patients, 58%, 35.5%, and 6.5% of the patients had grade 1, grade 2, and grade 3 of skin damage, respectively. There was no statistically significant relationship between regional skin burns and factors such as average tangential field size, internal mammary field, chemotherapy, prior history of diseases, tamoxifen use, previous radiotherapy in breast area, or skin type (p>0.05). However, there was a significant relationship between skin burns and presence of supraclavicular field (p=0.05). Conclusion Considering the significant relationship between skin burn and supraclavicular field, special attention needs to be paid to factors affecting the treatment planning of supraclavicular field such as field size and photon energy. |
topic |
Breast cancer Radiotherapy Skin Burns Breast Conserving Surgery Surgery |
url |
http://ijmp.mums.ac.ir/article_3568_87ce7e79549d61eb0eb0515cd94739d7.pdf |
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