Association between lifestyle factors and quality-adjusted life years in the EPIC-NL cohort.
The aim of our study was to relate four modifiable lifestyle factors (smoking status, body mass index, physical activity and diet) to health expectancy, using quality-adjusted life years (QALYs) in a prospective cohort study. Data of the prospective EPIC-NL study were used, including 33,066 healthy...
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doaj-9686fe2d106e4d92b0f271b52e7a79832020-11-25T01:51:46ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-01911e11148010.1371/journal.pone.0111480Association between lifestyle factors and quality-adjusted life years in the EPIC-NL cohort.Heidi P FransenAnne M MayJoline W J BeulensEllen A StruijkG Ardine de WitJolanda M A BoerN Charlotte Onland-MoretJeljer HoekstraYvonne T van der SchouwH Bas Bueno-de-MesquitaPetra H M PeetersThe aim of our study was to relate four modifiable lifestyle factors (smoking status, body mass index, physical activity and diet) to health expectancy, using quality-adjusted life years (QALYs) in a prospective cohort study. Data of the prospective EPIC-NL study were used, including 33,066 healthy men and women aged 20-70 years at baseline (1993-7), followed until 31-12-2007 for occurrence of disease and death. Smoking status, body mass index, physical activity and adherence to a Mediterranean-style diet (excluding alcohol) were investigated separately and combined into a healthy lifestyle score, ranging from 0 to 4. QALYs were used as summary measure of healthy life expectancy, combining a person's life expectancy with a weight for quality of life when having a chronic disease. For lifestyle factors analyzed separately the number of years living longer in good health varied from 0.12 year to 0.84 year, after adjusting for covariates. A combination of the four lifestyle factors was positively associated with higher QALYs (P-trend <0.0001). A healthy lifestyle score of 4 compared to a score of 0 was associated with almost a 2 years longer life in good health (1.75 QALYs [95% CI 1.37, 2.14]).http://europepmc.org/articles/PMC4219750?pdf=render |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Heidi P Fransen Anne M May Joline W J Beulens Ellen A Struijk G Ardine de Wit Jolanda M A Boer N Charlotte Onland-Moret Jeljer Hoekstra Yvonne T van der Schouw H Bas Bueno-de-Mesquita Petra H M Peeters |
spellingShingle |
Heidi P Fransen Anne M May Joline W J Beulens Ellen A Struijk G Ardine de Wit Jolanda M A Boer N Charlotte Onland-Moret Jeljer Hoekstra Yvonne T van der Schouw H Bas Bueno-de-Mesquita Petra H M Peeters Association between lifestyle factors and quality-adjusted life years in the EPIC-NL cohort. PLoS ONE |
author_facet |
Heidi P Fransen Anne M May Joline W J Beulens Ellen A Struijk G Ardine de Wit Jolanda M A Boer N Charlotte Onland-Moret Jeljer Hoekstra Yvonne T van der Schouw H Bas Bueno-de-Mesquita Petra H M Peeters |
author_sort |
Heidi P Fransen |
title |
Association between lifestyle factors and quality-adjusted life years in the EPIC-NL cohort. |
title_short |
Association between lifestyle factors and quality-adjusted life years in the EPIC-NL cohort. |
title_full |
Association between lifestyle factors and quality-adjusted life years in the EPIC-NL cohort. |
title_fullStr |
Association between lifestyle factors and quality-adjusted life years in the EPIC-NL cohort. |
title_full_unstemmed |
Association between lifestyle factors and quality-adjusted life years in the EPIC-NL cohort. |
title_sort |
association between lifestyle factors and quality-adjusted life years in the epic-nl cohort. |
publisher |
Public Library of Science (PLoS) |
series |
PLoS ONE |
issn |
1932-6203 |
publishDate |
2014-01-01 |
description |
The aim of our study was to relate four modifiable lifestyle factors (smoking status, body mass index, physical activity and diet) to health expectancy, using quality-adjusted life years (QALYs) in a prospective cohort study. Data of the prospective EPIC-NL study were used, including 33,066 healthy men and women aged 20-70 years at baseline (1993-7), followed until 31-12-2007 for occurrence of disease and death. Smoking status, body mass index, physical activity and adherence to a Mediterranean-style diet (excluding alcohol) were investigated separately and combined into a healthy lifestyle score, ranging from 0 to 4. QALYs were used as summary measure of healthy life expectancy, combining a person's life expectancy with a weight for quality of life when having a chronic disease. For lifestyle factors analyzed separately the number of years living longer in good health varied from 0.12 year to 0.84 year, after adjusting for covariates. A combination of the four lifestyle factors was positively associated with higher QALYs (P-trend <0.0001). A healthy lifestyle score of 4 compared to a score of 0 was associated with almost a 2 years longer life in good health (1.75 QALYs [95% CI 1.37, 2.14]). |
url |
http://europepmc.org/articles/PMC4219750?pdf=render |
work_keys_str_mv |
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