Differential macrophage activation alters the expression profile of NTPDase and ecto-5'-nucleotidase.

Differential macrophage activation alters the expression profile of NTPDase and ecto-5'-nucleotidase.

Macrophages are key elements in the inflammatory process, whereas depending on the micro-environmental stimulation they exhibit a pro-inflammatory (classical/M1) or an anti-inflammatory/reparatory (alternative/M2) phenotype. Extracellular ATP can act as a danger signal whereas adenosine generally se...

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Main Authors: Rafael Fernandes Zanin, Elizandra Braganhol, Letícia Scussel Bergamin, Luís Felipe Ingrassia Campesato, Alfeu Zanotto Filho, José Cláudio Fonseca Moreira, Fernanda Bueno Morrone, Jean Sévigny, Maria Rosa Chitolina Schetinger, Angela Terezinha de Souza Wyse, Ana Maria Oliveira Battastini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3278434?pdf=render

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