Matriptase zymogen supports epithelial development, homeostasis and regeneration

Matriptase zymogen supports epithelial development, homeostasis and regeneration

Abstract Background Matriptase is a membrane serine protease essential for epithelial development, homeostasis, and regeneration, as well as a central orchestrator of pathogenic pericellular signaling in the context of inflammatory and proliferative diseases. Matriptase is an unusual protease in tha...

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Bibliographic Details
Main Authors: Stine Friis, Daniel Tadeo, Sylvain M. Le-Gall, Henrik Jessen Jürgensen, Katiuchia Uzzun Sales, Eric Camerer, Thomas H. Bugge
Format: Article
Language:English
Published: BMC 2017-06-01
Series:BMC Biology
Subjects:
Development
Cell surface proteolysis
Epithelial cell signaling
Zymogen activity
Online Access:http://link.springer.com/article/10.1186/s12915-017-0384-4

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http://link.springer.com/article/10.1186/s12915-017-0384-4

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