Effects of Bailing capsule combined with irbesartan on oxidative stress, inflammatory response and immune function in patients with diabetic nephropathy
Objective: To explore the effects of Bailing capsule combined with irbesartan on oxidative stress, inflammatory response and immune function in patients with diabetic nephropathy. Methods: 142 patients with diabetic nephropathy admitted to our hospital from April 2017 to July 2018 were selected a...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Editorial Board of Journal of Hainan Medical University
2019-05-01
|
Series: | Journal of Hainan Medical University |
Subjects: | |
Online Access: | http://www.hnykdxxb.com/PDF/201909/08.pdf |
Summary: | Objective: To explore the effects of Bailing capsule combined with irbesartan on oxidative
stress, inflammatory response and immune function in patients with diabetic nephropathy.
Methods: 142 patients with diabetic nephropathy admitted to our hospital from April 2017 to
July 2018 were selected as the study subjects. 71 cases in the control group and 71 cases in the
observation group were randomly assigned. The renal function, oxidative stress, inflammation
and immune indexes of two groups of patients with diabetic nephropathy were compared
and analyzed. Results: After treatment, the levels of BUN, SCr, UARE, ROS, AOPPS, TNF-α, CRP and CD8+ of DN patients in both groups decreased significantly compared withthose before the treatment, while the levels of SOD, CD4+, CD4+/CD8+ increased significantly
compared with those before the treatment; and the levels of BUN, SCr, UARE, ROS, AOPPS,
TNF-α, CRP and CD8+ in the observation group were significantly lower than those in the
control group, while the levels of SOD, CD4+, CD4+/CD8+ in the observation group were
significantly higher than those in the control group. Conclusions: Bailing capsule combined
with irbesartan in the treatment of diabetic nephropathy can effectively improve the renal
function, oxidize inflammatory reaction and enhance the immune function of patients, which
has clinical significance.
|
---|---|
ISSN: | 1007-1237 1007-1237 |