Adriamycin - efficacy and possible adverse effects
Adriamycin (doxorubicin) is a chemical substance in the anthracycline class with a wide range of applications in oncology and hematology. The mechanism of action of Adriamycin is related to formation of irregular bonds between nucleobases of DNA and inhibition of key enzymes of DNA synthesis - topoi...
Main Authors: | , |
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Format: | Article |
Language: | deu |
Published: |
Sciendo
2016-03-01
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Series: | Current Problems of Psychiatry |
Subjects: | |
Online Access: | https://doi.org/10.1515/cpp-2016-0006 |
Summary: | Adriamycin (doxorubicin) is a chemical substance in the anthracycline class with a wide range of applications in oncology and hematology. The mechanism of action of Adriamycin is related to formation of irregular bonds between nucleobases of DNA and inhibition of key enzymes of DNA synthesis - topoisomerase I and II as well as to formation of free radicals damaging DNA. |
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ISSN: | 2353-8627 |