Adriamycin - efficacy and possible adverse effects

Adriamycin (doxorubicin) is a chemical substance in the anthracycline class with a wide range of applications in oncology and hematology. The mechanism of action of Adriamycin is related to formation of irregular bonds between nucleobases of DNA and inhibition of key enzymes of DNA synthesis - topoi...

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Main Authors:	Pedrycz Agnieszka, Kramkowska Agnieszka
Format:	Article
Language:	deu
Published:	Sciendo 2016-03-01
Series:	Current Problems of Psychiatry
Subjects:	adriamycin cardiotoxicity hepatotoxicity
Online Access:	https://doi.org/10.1515/cpp-2016-0006

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spelling	doaj-96cfe7e03661479dbcafbf2a1bbec21d2021-09-06T19:19:44ZdeuSciendoCurrent Problems of Psychiatry2353-86272016-03-01171384610.1515/cpp-2016-0006cpp-2016-0006Adriamycin - efficacy and possible adverse effectsPedrycz Agnieszka0Kramkowska Agnieszka1Histology and Embryology Department with the Experimental Cytology Laboratory of Medical University of LublinHistology and Embryology Department with the Experimental Cytology Laboratory of Medical University of LublinAdriamycin (doxorubicin) is a chemical substance in the anthracycline class with a wide range of applications in oncology and hematology. The mechanism of action of Adriamycin is related to formation of irregular bonds between nucleobases of DNA and inhibition of key enzymes of DNA synthesis - topoisomerase I and II as well as to formation of free radicals damaging DNA.https://doi.org/10.1515/cpp-2016-0006adriamycincardiotoxicityhepatotoxicity
collection	DOAJ
language	deu
format	Article
sources	DOAJ
author	Pedrycz Agnieszka Kramkowska Agnieszka
spellingShingle	Pedrycz Agnieszka Kramkowska Agnieszka Adriamycin - efficacy and possible adverse effects Current Problems of Psychiatry adriamycin cardiotoxicity hepatotoxicity
author_facet	Pedrycz Agnieszka Kramkowska Agnieszka
author_sort	Pedrycz Agnieszka
title	Adriamycin - efficacy and possible adverse effects
title_short	Adriamycin - efficacy and possible adverse effects
title_full	Adriamycin - efficacy and possible adverse effects
title_fullStr	Adriamycin - efficacy and possible adverse effects
title_full_unstemmed	Adriamycin - efficacy and possible adverse effects
title_sort	adriamycin - efficacy and possible adverse effects
publisher	Sciendo
series	Current Problems of Psychiatry
issn	2353-8627
publishDate	2016-03-01
description	Adriamycin (doxorubicin) is a chemical substance in the anthracycline class with a wide range of applications in oncology and hematology. The mechanism of action of Adriamycin is related to formation of irregular bonds between nucleobases of DNA and inhibition of key enzymes of DNA synthesis - topoisomerase I and II as well as to formation of free radicals damaging DNA.
topic	adriamycin cardiotoxicity hepatotoxicity
url	https://doi.org/10.1515/cpp-2016-0006
work_keys_str_mv	AT pedryczagnieszka adriamycinefficacyandpossibleadverseeffects AT kramkowskaagnieszka adriamycinefficacyandpossibleadverseeffects
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Adriamycin - efficacy and possible adverse effects

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