Drug repositioning by kernel-based integration of molecular structure, molecular activity, and phenotype data.

Drug repositioning by kernel-based integration of molecular structure, molecular activity, and phenotype data.

Computational inference of novel therapeutic values for existing drugs, i.e., drug repositioning, offers the great prospect for faster and low-risk drug development. Previous researches have indicated that chemical structures, target proteins, and side-effects could provide rich information in drug...

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Bibliographic Details
Main Authors: Yongcui Wang, Shilong Chen, Naiyang Deng, Yong Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3823875?pdf=render

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