Aptasensors Based on Stripping Voltammetry

• Main Authors: Wenjing Qi, Di Wu, Guobao Xu, Jacques Nsabimana, Anaclet Nsabimana
• Format: Article
• Language: English
• Published: MDPI AG 2016-07-01
• Series: Chemosensors
• Subjects: aptasensors; stripping voltammetry; aptamer; signal amplification
• Online Access: http://www.mdpi.com/2227-9040/4/3/12

Aptasensors based on stripping voltammetry exhibit several advantages, such as high sensitivity and multi-target detection from stripping voltammetric technology, and high selectivity from the specific binding of apamers with targets. This review comprehensively discusses the recent accomplishments in signal amplification strategies based on nanomaterials, such as metal nanoparticles, semiconductor nanoparticles, and nanocomposite materials, which are detected by stripping voltammetry after suitable dissolution. Focus will be put in discussing multiple amplification strategies that are widely applied in aptasensors for small biomolecules, proteins, disease markers, and cancer cells.