DIAGNOSIS AND TREATMENT OF PATIENTS WITH SEVERE HYPERCHOLESTEROLEMIA IN REAL OUTPATIENT PRACTICE (ACCORDING TO THE RECVASA REGISTRY)

• Main Authors: A. I. Ershova, A. N. Meshkov, S. S. Yakushin, M. M. Loukianov, K. A. Moseychuk, S. Yu. Martsevich, A. V. Zagrebelnyy, A. N. Vorobyev, K. G. Pereverzeva, E. A. Pravkina, A. N. Kozminskiy, S. A. Boytsov
• Format: Article
• Language: English
• Published: Stolichnaya Izdatelskaya Kompaniya 2015-09-01
• Series: Racionalʹnaâ Farmakoterapiâ v Kardiologii
• Subjects: гиперхолестеринемия; статины; амбулаторно-поликлиническая практика
• Online Access: http://www.rpcardio.ru/jour/article/view/286

<p>Hypercholesterolemia is a proven risk factor for atherosclerotic cardiovascular diseases and for their complications.</p><p><strong>Aim.</strong> To assess the quality of diagnosis and treatment of patients with severe hypercholesterolemia (total cholesterol &gt;6.2 mmol/L) in the real outpatient practice.</p><p><strong>Material and methods.</strong> All patients with a diagnosis of arterial hypertension, ischemic heart disease, chronic heart failure, atrial fibrillation applied to primary care physicians or cardiologists in one of the randomly selected out-patient clinic of Ryazan in March-May 2012 and included into the RECVASA registry were enrolled into the study group (n=1642).</p><p><strong>Results.</strong> The group of patients with severe hypercholesterolemia consisted of 561 (44%) patients at the age of 67 (59-75) years [Me (25% -75%)]. At that, diagnosis of hyperlipidemia was indicated only in 9% of outpatient cards. Data of one or more blood chemistries including low density cholesterol (LDC) levels were presented only in 7% of outpatient cards. 83.7% of patients with severe hypercholesterolemia were classified as patients at high or very high cardiovascular risk, but statins were recommended only to 17.8% of them. Statins were mainly recommended in moderate doses; only one patient took atorvastatin 40 mg per day. Blood LDC levels were examined only in 5% of patients during statins therapy; nobody of them reached target LDC levels.</p><p><strong>Conclusion.</strong> The study data revealed the presence of a high prevalence of severe hypercholesterolemia in patients with cardiovascular diseases and poor quality of diagnosis and treatment in these patients in the real outpatient practice.</p>