Protease-Activated Receptors in the Intestine: Focus on Inflammation and Cancer

Protease-activated receptors (PARs) belong to the G protein-coupled receptor (GPCR) family. Compared to other GPCRs, the specificity of the four PARs is the lack of physiologically soluble ligands able to induce their activation. Indeed, PARs are physiologically activated after proteolytic cleavage...

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Bibliographic Details
Main Authors: Morgane Sébert, Nuria Sola-Tapias, Emmanuel Mas, Frédérick Barreau, Audrey Ferrand
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Endocrinology
Subjects:
gut
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00717/full