Monitoring Protein Dynamics in Protein O-Mannosyltransferase Mutants In Vivo by Tandem Fluorescent Protein Timers

Monitoring Protein Dynamics in Protein O-Mannosyltransferase Mutants In Vivo by Tandem Fluorescent Protein Timers

For proteins entering the secretory pathway, a major factor contributing to maturation and homeostasis is glycosylation. One relevant type of protein glycosylation is O-mannosylation, which is essential and evolutionarily-conserved in fungi, animals, and humans. Our recent proteome-wide study in the...

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Bibliographic Details
Main Authors: Joan Castells-Ballester, Ewa Zatorska, Matthias Meurer, Patrick Neubert, Anke Metschies, Michael Knop, Sabine Strahl
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Molecules
Subjects:
glycosylation
mannosyltransferase
fluorescent protein timers
secretory pathway
O-mannosyl glycans
protein turnover
Saccharomyces cerevisiae
PMT1
PMT2
PMT4
yeast
Online Access:http://www.mdpi.com/1420-3049/23/10/2622

Internet

http://www.mdpi.com/1420-3049/23/10/2622

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