Targeting the JAK/STAT Signaling Pathway Using Phytocompounds for Cancer Prevention and Therapy
Cancer is a prevalent cause of mortality around the world. Aberrated activation of Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathway promotes tumorigenesis. Natural agents, including phytochemicals, exhibit potent anticancer activities via various mechanism...
Main Authors: | Sankhadip Bose, Sabyasachi Banerjee, Arijit Mondal, Utsab Chakraborty, Joshua Pumarol, Courtney R. Croley, Anupam Bishayee |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-06-01
|
Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/9/6/1451 |
Similar Items
-
Suppression of Autoimmune Arthritis by Small Molecule Inhibitors of the JAK/STAT Pathway
by: Charles J. Malemud
Published: (2010-05-01) -
Oncostatin M receptor β deficiency attenuates atherogenesis by inhibiting JAK2/STAT3 signaling in macrophages
by: Xin Zhang, et al.
Published: (2017-05-01) -
Activity of JAK/STAT and NF-kB in patients with axial spondyloarthritis
by: Jerzy Świerkot, et al.
Published: (2015-12-01) -
“Do We Know Jack” About JAK? A Closer Look at JAK/STAT Signaling Pathway
by: Emira Bousoik, et al.
Published: (2018-07-01) -
Phytochemicals Targeting JAK–STAT Pathways in Inflammatory Bowel Disease: Insights from Animal Models
by: Sun Young Moon, et al.
Published: (2021-05-01)