Missing tumor measurement (TM) data in the search for alternative TM-based endpoints in cancer clinical trials
Purpose: Missing data commonly occur in cancer clinical trials (CCT) and may hinder the search for alternative trial endpoints. We consider reasons for missing tumor measurement (TM) data in CCT and how missing TM data are typically handled. We explore the potential impact of missing TM data on pred...
Main Authors: | Ming-Wen An, Jun Tang, Axel Grothey, Daniel J. Sargent, Fang-Shu Ou, Sumithra J. Mandrekar |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-03-01
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Series: | Contemporary Clinical Trials Communications |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2451865419302546 |
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