Missing tumor measurement (TM) data in the search for alternative TM-based endpoints in cancer clinical trials

Purpose: Missing data commonly occur in cancer clinical trials (CCT) and may hinder the search for alternative trial endpoints. We consider reasons for missing tumor measurement (TM) data in CCT and how missing TM data are typically handled. We explore the potential impact of missing TM data on pred...

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Bibliographic Details
Main Authors: Ming-Wen An, Jun Tang, Axel Grothey, Daniel J. Sargent, Fang-Shu Ou, Sumithra J. Mandrekar
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Contemporary Clinical Trials Communications
Online Access:http://www.sciencedirect.com/science/article/pii/S2451865419302546

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