High-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in Kenya

Here, Nelson et al. use amplicon next-generation sequencing of two P. falciparum polymorphic gene regions to investigate the genetic similarity of parasite populations across time and space in a pediatric cohort in Kenya. They identify both micro- and macro-scale structuring of malaria parasites in...

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Main Authors:	Cody S. Nelson, Kelsey M. Sumner, Elizabeth Freedman, Joseph W. Saelens, Andrew A. Obala, Judith N. Mangeni, Steve M. Taylor, Wendy P. O’Meara
Format:	Article
Language:	English
Published:	Nature Publishing Group 2019-12-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-019-13578-4

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spelling	doaj-9781d83f0937441888046a9a8e2129112021-05-11T11:49:57ZengNature Publishing GroupNature Communications2041-17232019-12-0110111310.1038/s41467-019-13578-4High-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in KenyaCody S. Nelson0Kelsey M. Sumner1Elizabeth Freedman2Joseph W. Saelens3Andrew A. Obala4Judith N. Mangeni5Steve M. Taylor6Wendy P. O’Meara7Duke Global Health Institute, Duke UniversityDepartment of Epidemiology, Gillings School of Global Public Health, University of North CarolinaDivision of Infectious Diseases, Duke University School of MedicineDivision of Infectious Diseases, Duke University School of MedicineSchool of Medicine, Moi University College of Health SciencesSchool of Nursing, Moi University College of Health SciencesDuke Global Health Institute, Duke UniversityDuke Global Health Institute, Duke UniversityHere, Nelson et al. use amplicon next-generation sequencing of two P. falciparum polymorphic gene regions to investigate the genetic similarity of parasite populations across time and space in a pediatric cohort in Kenya. They identify both micro- and macro-scale structuring of malaria parasites in this high-transmission setting, which could inform future intervention strategies.https://doi.org/10.1038/s41467-019-13578-4
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Cody S. Nelson Kelsey M. Sumner Elizabeth Freedman Joseph W. Saelens Andrew A. Obala Judith N. Mangeni Steve M. Taylor Wendy P. O’Meara
spellingShingle	Cody S. Nelson Kelsey M. Sumner Elizabeth Freedman Joseph W. Saelens Andrew A. Obala Judith N. Mangeni Steve M. Taylor Wendy P. O’Meara High-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in Kenya Nature Communications
author_facet	Cody S. Nelson Kelsey M. Sumner Elizabeth Freedman Joseph W. Saelens Andrew A. Obala Judith N. Mangeni Steve M. Taylor Wendy P. O’Meara
author_sort	Cody S. Nelson
title	High-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in Kenya
title_short	High-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in Kenya
title_full	High-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in Kenya
title_fullStr	High-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in Kenya
title_full_unstemmed	High-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in Kenya
title_sort	high-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in kenya
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2019-12-01
description	Here, Nelson et al. use amplicon next-generation sequencing of two P. falciparum polymorphic gene regions to investigate the genetic similarity of parasite populations across time and space in a pediatric cohort in Kenya. They identify both micro- and macro-scale structuring of malaria parasites in this high-transmission setting, which could inform future intervention strategies.
url	https://doi.org/10.1038/s41467-019-13578-4
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High-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in Kenya

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