Visualization and identification of IL-7 producing cells in reporter mice.

Visualization and identification of IL-7 producing cells in reporter mice.

Interleukin-7 (IL-7) is required for lymphocyte development and homeostasis although the actual sites of IL-7 production have never been clearly identified. We produced a bacterial artificial chromosome (BAC) transgenic mouse expressing ECFP in the Il7 locus. The construct lacked a signal peptide an...

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Bibliographic Details
Main Authors: Renata I Mazzucchelli, Søren Warming, Scott M Lawrence, Masaru Ishii, Mehrnoosh Abshari, A Valance Washington, Lionel Feigenbaum, Andrew C Warner, Davis J Sims, Wen Qing Li, Julie A Hixon, Daniel H D Gray, Benjamin E Rich, Matthew Morrow, Miriam R Anver, James Cherry, Dieter Naf, Lawrence R Sternberg, Daniel W McVicar, Andrew G Farr, Ronald N Germain, Keith Rogers, Nancy A Jenkins, Neal G Copeland, Scott K Durum
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2770321?pdf=render

Internet

http://europepmc.org/articles/PMC2770321?pdf=render

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