Nrf2 activation supports cell survival during hypoxia and hypoxia/reoxygenation in cardiomyoblasts; the roles of reactive oxygen and nitrogen species

Nrf2 activation supports cell survival during hypoxia and hypoxia/reoxygenation in cardiomyoblasts; the roles of reactive oxygen and nitrogen species

Adaptive mechanisms involving upregulation of cytoprotective genes under the control of transcription factors such as Nrf2 exist to protect cells from permanent damage and dysfunction under stress conditions. Here we explore of the hypothesis that Nrf2 activation by reactive oxygen and nitrogen spe...

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Bibliographic Details
Main Authors: Rajitha T Kolamunne, Irundika HK Dias, Ann B Vernallis, Melissa M Grant, Helen R Griffiths
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Redox Biology
Subjects:
Adaptive
MnTBap
L-NAME
RNS
ROS
Glutathione
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231713000608

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