Camptothecin Induces PD-L1 and Immunomodulatory Cytokines in Colon Cancer Cells

Camptothecin Induces PD-L1 and Immunomodulatory Cytokines in Colon Cancer Cells

<b>Background:</b> Immunotherapy has changed the options for the treatment of various cancer types, but not colon cancer. Current checkpoint blockade approaches are ineffective in a large proportion of colon cancer cases, necessitating studies to elucidate its mechanisms and to identify...

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Bibliographic Details
Main Authors: Deepa Bedi, Henry J. Henderson, Upender Manne, Temesgen Samuel
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Medicines
Subjects:
camptothecin
colon cancer
cytokine
PD-L1
immunotherapy
topoisomerase inhibition
Online Access:https://www.mdpi.com/2305-6320/6/2/51

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