Mutant p53 and Twist1 Co-Expression Predicts Poor Prognosis and Is an Independent Prognostic Factor in Breast Cancer

Mutant p53 and Twist1 Co-Expression Predicts Poor Prognosis and Is an Independent Prognostic Factor in Breast Cancer

PurposeThe basic helix-loop-helix transcription factor (bHLH) transcription factor Twist1 plays a key role in embryonic development and tumorigenesis. p53 is a frequently mutated tumor suppressor in cancer. Both proteins play a key and significant role in breast cancer tumorigenesis. However, the re...

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Bibliographic Details
Main Authors: Yong-Qu Zhang, Fan Zhang, Yun-Zhu Zeng, Min Chen, Wen-He Huang, Jun-Dong Wu, Wei-Ling Chen, Wen-Liang Gao, Jing-Wen Bai, Rui-Qin Yang, Huan-Cheng Zeng, Xiao-Long Wei, Guo-Jun Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Oncology
Subjects:
mutant p53
Twist1
breast cancer
independent prognostic factor
poor prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.628814/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.628814/full

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