Reliability of malondialdehyde as a biomarker of oxidative stress in psychological disorders

Despite very wide variations of malondialdehyde (MDA) concentrations in biological samples, it is still used as a biomarker of oxidative stress in clinical investigations. In the current perspective study, we aimed to summarize a number of critical analytical points for determination of MDA. Technic...

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Bibliographic Details
Main Authors: Khalil Ansarin, Maryam Khoubnasabjafari, Abolghasem Jouyban
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2015-08-01
Series:BioImpacts
Subjects:
Online Access:http://journals.tbzmed.ac.ir/BI/PDF/BI-5-123.pdf
Description
Summary:Despite very wide variations of malondialdehyde (MDA) concentrations in biological samples, it is still used as a biomarker of oxidative stress in clinical investigations. In the current perspective study, we aimed to summarize a number of critical analytical points for determination of MDA. Technical problems and controversial findings in healthy people and some psychiatric disorders reveal that the reliability of MDA as a biomarker of oxidative stress needs to be re-evaluated by experts.
ISSN:2228-5652
2228-5660