ADGRA1 negatively regulates energy expenditure and thermogenesis through both sympathetic nervous system and hypothalamus–pituitary–thyroid axis in male mice
Abstract Adhesion G protein-coupled receptor A1 (ADGRA1, also known as GPR123) belongs to the G protein-coupled receptors (GPCRs) family and is well conserved in the vertebrate lineage. However, the structure of ADGRA1 is unique and its physiological function remains unknown. Previous studies have s...
Main Authors: | Xiao-Hong Zhang, Ling-Yun Tang, Xi-Yi Wang, Chun-Ling Shen, Wen-Feng Xiong, Yan Shen, Ying-Han Wan, You-Bing Wu, Yi-Cheng Wang, Hong-Xin Zhang, Shun-Yuan Lu, Jian Fei, Zhu-Gang Wang |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-04-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-021-03634-7 |
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