Liraglutide Ameliorates Erectile Dysfunction via Regulating Oxidative Stress, the RhoA/ROCK Pathway and Autophagy in Diabetes Mellitus

Liraglutide Ameliorates Erectile Dysfunction via Regulating Oxidative Stress, the RhoA/ROCK Pathway and Autophagy in Diabetes Mellitus

BackgroundErectile dysfunction (ED) occurs more frequently and causes a worse response to the first-line therapies in diabetics compared with nondiabetic men. Corpus cavernosum vascular dysfunction plays a pivotal role in the occurrence of diabetes mellitus ED (DMED). The aim of this study was to in...

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Bibliographic Details
Main Authors: Penghui Yuan, Delin Ma, Xintao Gao, Jiaxing Wang, Rui Li, Zhuo Liu, Tao Wang, Shaogang Wang, Jihong Liu, Xiaming Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Pharmacology
Subjects:
liraglutide
diabetes mellitus
erectile dysfunction
oxidative stress
autophagy
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.01257/full

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