Systematic review and meta-analysis of the relationship between EPHX1 polymorphisms and colorectal cancer risk.
BACKGROUND: Microsomal epoxide hydrolase (EPHX1) plays an important role in both the activation and detoxification of PAHs, which are carcinogens found in cooked meat and tobacco smoking. Polymorphisms at exons 3 and 4 of the EPHX1 gene have been reported to be associated with variations in EPHX1 ac...
Main Authors: | Fei Liu, Ding Yuan, Yonggang Wei, Wentao Wang, Lvnan Yan, Tianfu Wen, Mingqing Xu, Jiayin Yang, Bo Li |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3426545?pdf=render |
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