Genetic Variation in the ASTN2 Locus in Cardiovascular, Metabolic and Psychiatric Traits: Evidence for Pleiotropy Rather Than Shared Biology

Genetic Variation in the ASTN2 Locus in Cardiovascular, Metabolic and Psychiatric Traits: Evidence for Pleiotropy Rather Than Shared Biology

Background: The link between cardiometabolic and psychiatric illness has long been attributed to human behaviour, however recent research highlights shared biological mechanisms. The <i>ASTN2</i> locus has been previously implicated in psychiatric and cardiometabolic traits, therefore th...

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Bibliographic Details
Main Authors: Olivia Burt, Keira J. A. Johnston, Nicholas Graham, Breda Cullen, Donald M. Lyall, Laura M. Lyall, Jill P. Pell, Joey Ward, Daniel J. Smith, Rona J. Strawbridge
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Genes
Subjects:
<i>ASTN2</i>
cardiovascular disease
metabolic disease
psychiatric illness
anhedonia
mood instability
Online Access:https://www.mdpi.com/2073-4425/12/8/1194

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