Short-Term Response to Infliximab in Rheumatoid Pattern Polyarthropathy Complicating Ulcerative Colitis
Ulcerative colitis (UC) is a progressive inflammatory disease (IBD) of the bowel which can be accompanied by extra-intestinal findings such as peripheral and axial arthropathies. Patients with UC sometimes display rheumatoid pattern polyarthropathy which is challenging to differ from rheumatoid arth...
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Cukurova University
2015-12-01
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doaj-980bcb5b5ff241518c7fd83193f690e82020-11-24T21:11:29ZengCukurova UniversityÇukurova Üniversitesi Tıp Fakültesi Dergisi0250-51502015-12-01404818821167681Short-Term Response to Infliximab in Rheumatoid Pattern Polyarthropathy Complicating Ulcerative Colitisilke Coskun Benlidayi0Erkan Kozanoglu1Emine Aygul Ortac2Department of Physical Medicine and Rehabilitation/Faculty of Medicine, Cukurova University/Adana/Turkey Department of Physical Medicine and Rehabilitation/Faculty of Medicine, Cukurova University/Adana/Turkey Department of Physical Medicine and Rehabilitation/Faculty of Medicine, Cukurova University/Adana/TurkeyUlcerative colitis (UC) is a progressive inflammatory disease (IBD) of the bowel which can be accompanied by extra-intestinal findings such as peripheral and axial arthropathies. Patients with UC sometimes display rheumatoid pattern polyarthropathy which is challenging to differ from rheumatoid arthritis. We describe a case with rheumatoid pattern polyarthropathy complicating UC and her favourable response to infliximab therapy. A 25-year-old female with a diagnosis of UC was admitted due to swelling and pain in multiple joints. Laboratory tests revealed elevated acute phase reactants. Since the patient was refractory to the combination therapy comprising methotrexate, sulphasalazine and steroid, she was started on an infliximab regimen. She experienced an improvement both in terms of pain scores and biochemical findings. The patient was asymptomatic with reduced acute phase reactants following a 6-month-course of anti-tumor necrosis factor (anti-TNF) therapy. Infliximab serves as an effective treatment option for the management of rheumatoid pattern peripheral polyarthritis associated with UC. [Cukurova Med J 2015; 40(4.000): 818-821]http://www.scopemed.org/fulltextpdf.php?mno=167681anti-TNFarthritisinfliximabpolyarthropathyulcerative colitis |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
ilke Coskun Benlidayi Erkan Kozanoglu Emine Aygul Ortac |
spellingShingle |
ilke Coskun Benlidayi Erkan Kozanoglu Emine Aygul Ortac Short-Term Response to Infliximab in Rheumatoid Pattern Polyarthropathy Complicating Ulcerative Colitis Çukurova Üniversitesi Tıp Fakültesi Dergisi anti-TNF arthritis infliximab polyarthropathy ulcerative colitis |
author_facet |
ilke Coskun Benlidayi Erkan Kozanoglu Emine Aygul Ortac |
author_sort |
ilke Coskun Benlidayi |
title |
Short-Term Response to Infliximab in Rheumatoid Pattern Polyarthropathy Complicating Ulcerative Colitis |
title_short |
Short-Term Response to Infliximab in Rheumatoid Pattern Polyarthropathy Complicating Ulcerative Colitis |
title_full |
Short-Term Response to Infliximab in Rheumatoid Pattern Polyarthropathy Complicating Ulcerative Colitis |
title_fullStr |
Short-Term Response to Infliximab in Rheumatoid Pattern Polyarthropathy Complicating Ulcerative Colitis |
title_full_unstemmed |
Short-Term Response to Infliximab in Rheumatoid Pattern Polyarthropathy Complicating Ulcerative Colitis |
title_sort |
short-term response to infliximab in rheumatoid pattern polyarthropathy complicating ulcerative colitis |
publisher |
Cukurova University |
series |
Çukurova Üniversitesi Tıp Fakültesi Dergisi |
issn |
0250-5150 |
publishDate |
2015-12-01 |
description |
Ulcerative colitis (UC) is a progressive inflammatory disease (IBD) of the bowel which can be accompanied by extra-intestinal findings such as peripheral and axial arthropathies. Patients with UC sometimes display rheumatoid pattern polyarthropathy which is challenging to differ from rheumatoid arthritis. We describe a case with rheumatoid pattern polyarthropathy complicating UC and her favourable response to infliximab therapy. A 25-year-old female with a diagnosis of UC was admitted due to swelling and pain in multiple joints. Laboratory tests revealed elevated acute phase reactants. Since the patient was refractory to the combination therapy comprising methotrexate, sulphasalazine and steroid, she was started on an infliximab regimen. She experienced an improvement both in terms of pain scores and biochemical findings. The patient was asymptomatic with reduced acute phase reactants following a 6-month-course of anti-tumor necrosis factor (anti-TNF) therapy. Infliximab serves as an effective treatment option for the management of rheumatoid pattern peripheral polyarthritis associated with UC. [Cukurova Med J 2015; 40(4.000): 818-821] |
topic |
anti-TNF arthritis infliximab polyarthropathy ulcerative colitis |
url |
http://www.scopemed.org/fulltextpdf.php?mno=167681 |
work_keys_str_mv |
AT ilkecoskunbenlidayi shorttermresponsetoinfliximabinrheumatoidpatternpolyarthropathycomplicatingulcerativecolitis AT erkankozanoglu shorttermresponsetoinfliximabinrheumatoidpatternpolyarthropathycomplicatingulcerativecolitis AT emineaygulortac shorttermresponsetoinfliximabinrheumatoidpatternpolyarthropathycomplicatingulcerativecolitis |
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1716753203375112192 |